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Conflict of interest: No conflict of interest P796 Human endogenous retroviruses (HERV)-H and -K sequences are hypomethylated and present in the circulating microvescicles of colon cancer patients Serena Del Bue 1 , Maria Dolci 1 , Letizia Tarantini 1 , Valentina Bollati 1 , Chiara Favero 1 , Sonia Villani 1 , Alberto Della Valle 2 , Rosalia Ticozzi 1 , Pasquale Ferrante 1 , Elena Parrello 1 , Filippo Crivelli 3 , Marco Bregni 4 1 1 1 1 1 1 2 1 1 1 3 4 1 University of Milan, Milano, Italy

In other studies, zinc deficiency exacerbates hepatic lipid metabolism, while Zn supplementation increases hepatocyte activity and improves lipid metabolism in the liver [77, 78]

This cascade of oxidative stress can lead to cellular dysfunction and damage, significantly impacting various tissues and organs [174, 175]

BCAA metabolism in pancreatic cancer affects lipid balance by regulating fatty acid import into mitochondria

Oxidative stress is the internal "wear and tear" caused by free radicalsunstable molecules that can damage cells if left unchecked