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Follow-up studies have found that serum IL-1 and IL-6 levels in the central and peripheral regions of patients with drug-resistant epilepsy decreased at 1 year after surgical treatment compared with those before surgery (148)

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Hormesis refers to the evolutionary conserved adaptive responses of all living organisms to mild environmental, nutritional, or even voluntary challenges, through which the system amends its tolerance to more toxic stress factors (Pruimboom and Muskiet, 2018)

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