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The most frequent symptoms are: Developmental delays Anaemia Loss of appetite Chronic vomiting Weight loss Low brain volume Spasms/cramps Apathy Irritability In the most severe instance, vitamin B12 deficiency can lead to respiratory failures and coma (51)

Q5: Is this medicine safe for people of all ages

Analysis scripts and notebooks used for this study are open-source and available from GitHub ( Any additional information required to reanalyze the data reported in this work paper is described in the Methods and available upon request from the corresponding authors