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Pilot PET study to assess the functional interplay between ABCB1 and ABCG2 at the human blood-brain barrier

[DOI] [PMC free article] [PubMed] [Google Scholar] 408.Avery J.C., Hoffmann P.R

During radiotherapy cancer cells are exposed to ionizing radiation which induces the production of ROS followed by irreversible damage to vital cellular structures including mitochondria and DNA which eventually lead to apoptosis and cell death (Smets, 1994