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But I suppose if the 2ml is coming from a different manufacturer from the 1ml it could have different additives

variation in experimental protocols

It makes manufacturer transparency and documented testing more important

There is a real biological basis for this

The length of the SSRs, when located within a coding region, can change translation by introducing a frameshift in the reading frame, or, when located in the proximity of a promoter, can modulate transcription either by altering the promoter sequence or by switching between alternative promoter sites

doi: 10.1007/s12263-009-0154-1 16 LindrosKOStowellAPikkarainenPSalaspuroM