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Simultaneously, NNMT inhibition preserves SAM the primary methyl-donor for epigenetic histone and DNA methylation reactions which has been shown to influence gene expression programmes governing adipogenesis, lipid storage, and energy expenditure in adipose tissue models

Testing TSH, T4, T3, and the two most common Hashimotos antibodies (TPO and TG antibodies you can read more about thyroid tests here ) is an important part of ensuring that the lifestyle changes you are making are both safe and helpful