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Molecular docking DFT optimized structure of carmustine and crystal structure of human reductase obtained from research collaboratory for structural bioinformatics (RCSB) protein data bank is taken for molecular docking simulation

When mitochondrial function becomes impaired, ROS production may increase while energy production becomes less efficient

In the study by Shrabek et al

Jalili A, Irani S, Mirfakhraie R

doi: 10.1016/j.ejogrb.2014.06.008 148 FangFNiKCaiYShangJZhangXXiongC

Manifestations of histamine release and/or peripheral vasodilation may include pruritus, flushing, red eyes, sweating, and/or orthostatic hypotension