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A couple of studies were able to demonstrate some autism patients who had decreased intake of the vitamin in their restricted diets 1,2

Additionally, B12 is water-soluble, meaning that the body naturally filters out what it has no use for

High doses (1,000 mcg/day) of oral methylcobalamin supplements appear to be as effective as hydroxycobalamin injections in normalizing vitamin B12 values in patients who have undergone Roux-en-Y gastric bypass surgery [55]

If anything other than sterile saline was added, it may have been a preservative that you had reacted to

For maintenance, adults get Vitamin B12 injections monthly

Malar J 8: 106