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Systemic treatment is centered around hyperglycemia, hypertension, and hyperlipidemia management.Citation 48 The most common ocular-specific treatment option in the proliferative and non-proliferative phase of DR is to target angiogenesis.Citation 48 , Citation 49 Anti-VEGF agents have become the standard of care to treat DME and is used frequently in the management of PDR

MS, IR-B, and PG: writingreview and editing

doi: 10.1155/2012/839298 77

Write down every injection date, the number of units drawn, the dose in milligrams, the injection site, and any notes about side effects or observations