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Elevated ACSL4 activity, increased ferritin expression, and restricted iron export further enhance the oxidative and iron-dependent milieu, enabling M1 macrophages to promote ferroptotic pressure on neighboring tumor cells (39)

Furthermore, the PI3K/Akt pathway [52], which regulates cell survival and proliferation, may contribute to the protective effects of collagen peptides against cellular senescence and apoptosis

LiTZhengJWangZXuLSunDSongHet alMaresin 1 improves cognitive decline and ameliorates inflammation and blood-brain barrier damage in rats with chronic cerebral hypoperfusion

Hays RD, Sherbourne CD, Mazel RM

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The compounds were eluted at a flow rate of 1.2 mL/min with mobile phase (0.25% acetic acid, 0.25% phosphoric acid, 9% acetonitrile, and 90.5% water)