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The four most common reasons are: pernicious anaemia (an autoimmune disorder of a lack of red blood cells due to the body not being to absorb enough vitamin B12) a vegetarian or vegan diet

This vitamin is required for proper development and function of your nerves, brain and blood cells

Moderately low serum B12 concentrations between 148 or 150 and 221pmol/L or 260pmol/L are often considered indicative of depleted or subclinical B12 deficiency

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Any clinical research initiatives must be conducted under the guidance of the relevant Institutional Review Board (IRB)

Further experience with the use of anti-CD38 antibodies in RRMM after prior treatment with daratumumab will stem from a current phase Ib trial of SC isatuximab in combination with Pd (NCT04045795) and for daratumumab from a phase II study in combination with Kd (NCT03871829)