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Little, A

The extensive use of urban lighting has profoundly transformed natural nighttime darkness, creating light pollution. Data indicate that over 80% of the global population resides in areas experiencing substantial light pollution, with these regions expanding at an annual rate of 2.2% ( Exposure levels vary across populations

These metabolic shifts are part of why measurements taken during acute illness are interpreted with caution

Yang Q, Mo C, Cui P, Zhou S, Qiu L, Jiang P, et al

eLife 10 , e62174 (2021)

Think of spinal discs like jelly donuts - when the outer ring tears, inner material can squeeze out and press on nerve roots