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Two independent controlled studies using the same dose concluded the effect was of little clinical significance and not likely to be of major therapeutic benefit. Because the negative studies matched the positive studies dose, the failure cannot be explained by underdosing

The sector exposure differences can significantly impact an ETF's performance, as each sector performs differently under various market conditions

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Moreover, the treatment of those cells with a specific c-Met inhibitor (PHA665752) reduced apoptosis indicating that it requires activation of the canonical receptor tyrosine kinase (Li et al., 2008a)