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Evidence level is high based on confirmed Phase 3 data

Getting out of bed without pain

Yi ZF, Cho SG, Zhao H, Wu Yy, Luo J, Li D, et al

Evidence that the Angiotensin IV (AT4) receptor is the enzyme insulin-regulated aminopeptidase

In addition, 41% of people treated with nirogacestat had tumor shrinkage, compared with 8% of people treated with a placebo

It promotes new blood vessel formation, stimulates keratinocyte and fibroblast migration into wound sites, and modulates the inflammatory response by reducing local levels of inflammatory cytokines all critical to healing after oral surgical procedures