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People with Asthma may still be eligible for IV GSH but there is a risk of it aggravating and causing an attack

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Finger Survey of Ophthalmology.2023

Metformin, an AMPK activator, inhibits TGF-1-induced myofibroblast differentiation by promoting AMPK expression, leading to myofibroblast deactivation and apoptosis, reduction in the expression of type I collagen, fibronectin (FN), and -SMA in fibroblasts, and downregulation of ECM protein levels, thereby slowing or reversing PF ( Ex vivo experiments using precision-cut lung slices from IPF patients and mouse models further confirmed saracatinibs ability to downregulate fibrotic genes, reduce collagen accumulation, and decrease -SMA-positive areas

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