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Hybrid agents combining tacrine and deferiprone have also been developed to target multiple AD-related pathways (312)

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These encompass palmar and solar keratosis, gastrointestinal symptoms such as vomiting and diarrhea, dermatological abnormalities, neuropathy, ischemic heart disease, cognitive impairment including confusion and memory loss, respiratory disorders, hormonal imbalance, compromised immune system function, and an increased risk of diabetes 64,66,67

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