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Larsen, A

Negative regulators of JAK/STAT signaling in rheumatoid arthritis and osteoarthritis

Abstract Disruption of the intestinal epithelial tight junction (TJ) barrier is a key pathogenic factor in numerous gastrointestinal (GI) disorders, including inflammatory bowel disease, irritable bowel syndrome, necrotizing enterocolitis, and enteric infections

It affects about one-third of people with lupus and can cause color loss in the fingers and toes, which first turn white or blue, followed by red with rewarming

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