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[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Doty RL, et al

With regard to the substantial clinical improvement criterion, the applicant asserted that SeptiCyte RAPID represents a substantial clinical improvement over existing technologies because SeptiCyte RAPID is the only technology to accurately differentiate sepsis versus non-infectious systemic inflammation in 1 hour, allowing for early, appropriate intervention in suspected sepsis patients and driving prompt source control investigation, while outperforming currently used sepsis diagnostic tools

It has a central role in nitric oxide signalling and has been implicated in many essential physiological processes and disease conditions

Anti-inflammatory potential of curcumin and quercetin in rats: role of oxidative stress, heme oxygenase-1 and TNF-alpha

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By increasing the production of ROS and diminishing antioxidant defenses, CB1 receptor activation exacerbates oxidative stress, contributing to hepatocyte damage and the progression of fibrosis (Tan et al