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GCLC knockout mice die within a month of birth due to the absence of hepatic GSH synthesis

It is the specific binding extrapolated to very high concentrations of radioligand, and so its value is almost always higher than any specific binding measured in your experiment

Studies investigating subpopulations within brain regions (i.e., input regions, cell types, projection targets) have utilized many techniques, including targeted expression of optogenetic tools, tracing strategies, and reporter animal models