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Making @fentyskin was a challenge to cover all bases and thinking of the many skin types that are out there! Rihanna wrote on Twitter

Therefore, providing a definitive answer proves challenging, primarily due to the wide array of mutations (identical alterations on both alleles, different mutations for each allele, or even classic heterozygosity)

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Long-term safety data in extended rodent studies (90+ days) would be essential before translating this to human protocols

Guarner J, Brandt ME

Epigenetics Epigenetics is the study of changes in gene expression that occur without altering the DNA sequence