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Three to 4 weeks later, LPS (Sigma, O55:B5, 5 mg/kg) was injected intraperitoneally and the brains were harvested 6 h later

Conversely, diminished ROS levels have been correlated with a hypoactive inflammatory response, which can subsequently result in immunosuppression

Significant degeneration and necrosis were observed in the neurons of the rats in the DM group, accompanied by pronounced hyperemia in the parenchyma and meningeal arteries

Moreover, LSD1 removes methyl groups from Dnmt1, thus contributing to its stability

The liver also exhibits the highest COMT activity, suggesting that it is the predominant organ responsible for methylation of ECs catechol moieties