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It secretes cyclic lipopeptides, such as surfactins, fengycins, and iturins, that disrupt the cell membranes of bacterial and fungal pathogens, leading to their lysis (Falardeau et al

For example, under continuous infusion pump drive, the release rate remains stable (e.g., morphine delivery, with a release error of less than 5% over 24 h) [89]

The cases of hereditary occurrence of CRC constitute only about 5% [28]

Thus, considering also the natural inhibition of endocytosis in the BBB barrier, it is possible that early in infection, only a few meningococci can cross the barrier through the transcellular route