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In fact, according to the Centers for Disease Control and Prevention (CDC), about 40.3% of American adults were obese in 2021-2023, highlighting the widespread need for effective weight management strategies

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They control mast cell differentiation, proliferation, function, and resolution of immune responses.[ref] MiRNAs have been shown to be upregulated in mast cell activation, and miRNAs can also suppress degranulation or cytokine release

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The Canadian research community has increasingly explored these combinations, particularly as weight loss medications become more accessible