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Its deficiency results in reduced NAD + synthesis and accumulation of its substrate, NAM, leading to increased NNMT activity and further decline in NAD + levels

This is just an average though and that brings me to the third fact

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While generally considered safe for use in research and by fitness enthusiasts, individual responses can vary

Adequate levels of B12 are essential for preventing anemia, maintaining energy levels, supporting cognitive function, and promoting overall health