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2011;668(Suppl 1):S7080

NRF2 is a pivotal transcription factor of PHGDH, and its SUMOylation promotes SSP by transcriptionally upregulating PHGDH, maintaining HCC tumorigenesis in response to metabolic stress [117]

Piperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in animal model of cognitive deficit like condition of Alzheimers disease

10.3233/JAD-170585 J

doi: 10.3389/fphar.2021.766082 267

In 2016, researchers first designed phosphate and pyrophosphate-containing linkers coupled with the well-established, cathepsin B sensitive, Val-Cit-PABA moiety aiming to deliver glucocorticoids