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239 [2022] issued by the Department of Human Resources and Education of the National Administration of Traditional Chinese Medicine), and the 2022 University-Level Scientific Research Project of Hunan University of Chinese Medicine (Document No

2020;217:e20192195

534,535,536,537 In addition to the two marketed drugs summarized in the previous section, tazemetostat (EPZ-6438) and valemetostat (DS-3201b), numerous novel EZH2 inhibitors are under investigation, with several advances in clinical studies, particularly compounds featuring the 2-pyridone moiety which encompass both bicyclic heteroaromatic and monocyclic aromatic rings

Omar SM, Ahmed MM, Khalil OA, Mady MM

Ran et al (105) encapsulated ginsenoside compound K in nanomicelles fabricated via ultrasonic self-assembly of O-carboxymethyl chitosan, N-isopropylacrylamide and thermoresponsive IR820