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Cancer Res (2019) 79(4_Supplement)

Because activated IKK can rapidly phosphorylate IBs, chemical inhibition of IKK or its genetic knockout (KO) has become an experimental approach to block NF-B mediated proliferation and migration of tumor cells and inflammatory response [3, 8, 9]

10.1017/jns.2016.41 89

Another possible contributing mechanism is maladaptive neuroplasticity, in which neuronal pathways adapt and conform pathologically to changes in auditory system nerve signaling