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Abstract To combat antibiotic resistance, one innovative approach, known as the metabolic state-driven approach, exploits the fact that exogenous nutrient metabolites can stimulate uptake of antibiotics

Cells were then exposed to NAC/urease combinations for 24 h

The elevation of p53 probably affects the expression of other critical genes and finally leads to apoptosis

Therefore, a proper combination of both elements into a single product could assure a better outcome than either the probiotics or prebiotics activity alone

This groundbreaking move marks the first time any U.S

Male mice that were given a low-protein diet from weaning until they reached sexual maturity showed elevated hepatic expression of genes related to the production of lipids and cholesterol (Carone et al., 2010)