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doi: 10.3389/fphys.2018.00044 64 AgarwalANallellaKPAllamaneniSSSaidTM

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The complexity of hEDS, involving multiple bodily systems and diverse manifestations such as chronic pain, dysautonomia, and gastrointestinal dysfunction, further complicates timely diagnosis [95]

In fact, inflammation produces an increase in oxidative stress, and the consequent cellular damage becomes a way to trigger inflammation

Therefore, it is necessary to systematically examine how amino acid metabolism regulates macrophage polarization and its role in autoimmune diseases within a network-based framework

This means looking at your hydration, your stress management, and your diet alongside your supplement routine