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Beyond lipid-lowering: effects of statins on cardiovascular and cerebrovascular diseases and cancer

Regulatory progress has been slowed by the need for more rigorous data on long-term safety, biodistribution, clearance mechanisms, and consistent efficacy across patient populations

Genetic variations in the PI3K-PTEN-AKT-mTOR pathway are associated with distant metastasis in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy

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Advanced imaging techniques combined with biochemical assays for lipid peroxidation products (e.g., specific isoprostanes) and iron speciation in cerebrospinal fluid or blood could enable earlier diagnosis and improved patient stratification

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