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Cuando la provisin de vitamina B12 es insuficiente, la replicacin de ADN se vuelve anormal y el defecto de replicacin cromosmica produce incapacidad por parte de las clulas de madurar y completar las divisiones nucleares, en tanto que la maduracin citoplasmtica contina en forma relativamente normal

According to Lindgren, it takes 3-6 months to see an upregulation, or increase, in the overall amount of GH isolates being produced by the pituitary gland

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They cause an imbalance between specific groups of bacteria and trigger the development of dysbacteriosis (Tulstrup et al., 2015)