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the review of Huddleston et al., 2014 and Leach et al., 2016)

10.1105/tpc.6.1.11 Plant Cell 113 VolokitaM.Rosilio-BramiT.RivkinN.ZikM

Photo by Innerbody Research Around 30-50% of American adults dont get enough sleep.1 The consequences of this insufficiency can be steep, as without a regular 7-8 hours rest per night, a person can find themselves at risk for depression, decreased cognitive function, and an increased risk of cardiovascular and endocrine dysfunction.2 For the many millions of people with sleep deficiency, a peptide called DSIP could be a solution, although some researchers might disagree

Prostaglandins, specifically PGE 2 , have been shown to increase in irradiated salivary glands, and mitigation of salivary gland damage was achieved with the anti-inflammatory drug Indomethacin 1,87

Hambley TW (2007) Developing new metal-based therapeutics: challenges and opportunities

In a cohort study of 80 male patients with alcoholic cirrhosis and 70 healthy male non-alcoholic controls, MDA levels, a known marker of lipid peroxidation, were significantly higher in those with alcoholic cirrhosis.Additionally, a negative correlation was found between MDA levels and the activities of antioxidant enzymes such as superoxide dismutase (SOD), GPx, and glutathione (GSH), indicating heightened oxidative stress and impaired antioxidant defense in ALD patients (79) ( Figure 1 )