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The clinical significance of this finding lies in the fact that while conventional anti-inflammatory therapies (such as corticosteroids) often carry the risk of broad-spectrum immunosuppression, natural products, by promoting the M1-to-M2 macrophage transition, essentially represent an immune modulation strategy

The same trend was seen in a 2021 study published in The New England Journal of Medicine

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it's useful if you're in an office that's poorly lit, but you still need to jumpstart that circadian rhythm early in the day