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Monitoring PpIX biosynthesis in vivo by real-time FL/PA duplex imaging As oxidative stress is a key to the synergistic effect of IIT and 5-ALA-PDT for enhanced therapeutic efficacy 37,47,48 , we explored the metabolic dynamics of PpIX and O 2 generation to validate the feasibility for PpIX synthesis regulation and optimizing treatment parameters in vivo

Deletion of the regulatory domain in the pyridoxal phosphate-dependent heme protein cystathionine beta-synthase alleviates the defect observed in a catalytic site mutant

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Atrichia caused by mutations in the vitamin D receptor gene is a phenocopy of generalized atrichia caused by mutations in the hairless gene

Glutathione, a natural antioxidant found in the body, is responsible for neutralizing free radicals, lowering oxidative stress, and enhancing skin clarity