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NAMPT and NRK1/2 are also localized to the nucleus and cytosol 48,83,84 , suggesting that only the final step of salvage is performed in the mitochondria, with a mitochondrial NMN transporter, Slc25a45, recently proposed 85

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Di Gaetano R, Gasparetto V, Padoan A, Callegari B, Candiotto L, Sanzari MC, et al

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A deficiency in B12 can lead to megaloblastic anemia, a condition characterized by the production of abnormally large and dysfunctional red blood cells