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Both selective AMYR agonists, and dual CTR and AMYR agonists such as sCT 5,6,7 , have demonstrated efficacy in controlling appetite and body weight, however this is not seen with a CTR-selective agonist 9

Peer-reviewed replication in Western journals concentrates on mechanism of action and in-vitro pharmacology rather than clinical efficacy

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This approach enabled high-sensitivity quantification of dynamic changes in BCL-2 mRNA levels, AR expression, AR pathway activity ( KLK3, TMPRSS2 ), and potential compensatory or bypass survival signaling (e.g., NR3C1 , i.e., GR) (Fig

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