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doi: 10.1182/blood.2020007899 189 SharmaANairRAchrejaAMittalAGuptaPBalakrishnanKet al

Expect body-composition shifts over months, not dramatic weight loss

10.1016/j.bmcl.2009.07.068 Bioorg

Researchers suggest that elevated gut pH, gut dysbiosis (i.e., a higher Firmicutes : Bacteroidetes ratio), obesity, or malabsorption might increase fecal SCFA, such as butyrate, which could have potential neurotoxic effects [25, 45, 46]

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We have summarized the physiological and pathological mechanisms related to ferroptosis in MASLD (Figure 1) and summarized relevant research evidence