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However, like a coin with two sides, we must carefully weigh the reported side effects and potential risks, as discussed in this review, against its benefits during ferroptosis therapy

Modulation of redox homeostasis by inhibition of MTHFD2 in colorectal cancer: Mechanisms and therapeutic implications

10.1111/j.1471-0528.1996.tb09641.x 48 CharoenviriyakulC.TakahashiY.MorishitaM.MatsumotoA.NishikawaM.TakakuraY

Ren Y, Mao X, Xu H, Dang Q, Weng S, Zhang Y, Chen S, Liu S, Ba Y, Zhou Z, et al

Heat shock protein 27 deficiency promotes ferrous ion absorption and enhances acyl-coenzyme a synthetase long-chain family member 4 stability to promote glioblastoma cell ferroptosis

Bioorg Med Chem Lett 74:128911 Pang Y, Liu X, Wang X et al (2022) Edaravone modulates neuronal GPX4/ACSL4/5-LOX to promote recovery after spinal cord injury