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Here, we used non-parametric testing that does not rely on data normality and that has been shown to limit the rate of false positives in neuroimaging studies 38

275 For example, more mtDNA mutations were observed in aged oocytes than in young ones, and the increased mutations inhibited the ovarian function, resulting in fewer available follicles and affecting female fertility

Results A total of 267 dysregulated metabolites were identified in patients with MMA, including 185 upregulated and 82 downregulated metabolites

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This is different from exposure to carcinogenic and genotoxic mycotoxins which can have a long-term negative impact on human health

In CNS diseases, necrotic apoptosis is involved in the pathological process of a variety of neurodegenerative diseases, including PD, amyotrophic lateral bundle sclerosis (ALS), multiple sclerosis (MS), and AD (Shi et al., 2023