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ALDH7A1 gene mutation and epilepsy The ALDH7A1 gene, located on chromosome 5q23.2, encodes antiquitin, which is responsible for catalyzing the dehydrogenation of -aminoadipic semialdehyde (-AASA)/piperideine 6-carboxylate (P6C)

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Otherwise, intra-abdominal hypertension adversely affects many organs, such as the brain, heart, lungs, kidneys, and gastrointestinal tract (Cullen et al., 1989), progressing to lethal levels