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Instead their mechanism of action is to temporarily disrupt anti-apoptotic pathways utilized by senescent cells for their survival

NAC (N-acetylcysteine) as precursor: Rather than supplementing glutathione directly, NAC provides the rate-limiting amino acid (cysteine) for endogenous glutathione synthesis

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This is supported in a study by Brignardello et al [214] that looked at gut permeability in asymptomatic, non-smoking obese volunteers and observed no differences compared to healthy controls

These are averages in trial participants, not guaranteed individual outcomes, and the Phase 3 figure comes from a sponsor announcement awaiting full peer-reviewed publication