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Description

Metabolic dysfunction-associated steatotic liver disease and the gut microbiome: pathogenic insights and therapeutic innovations

Funding : This study was supported by the Ramalingaswami Reentry Fellowship (Grant number: D.O

Further supporting global heterogeneity, a 2024 metaanalysis published in Nature reported PD prevalence estimates ranging from 49 per 100,000 in SubSaharan Africa to 1081 per 100,000 in Latin America [39], figures that suggest even greater regional variability than captured in GBD estimates

Research indicates that changes in the gut microbiome can damage the liver by inducing inflammatory responses, exacerbating liver fibrosis, and affecting host metabolism (Martnez-Montoro et al., 2022