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M2 macrophages M2, or alternatively activated, macrophages are generally induced by interleukin-4 (IL-4) and IL-13, although various M2-like subtypes have been described

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Additionally, investigations revealing catalases modulation of oxidative stress-induced channel activations underscore the enzymes crucial role in preserving mitochondrial function and neuronal viability, suggesting a significant impact on the pathogenesis of PD and associated sensory disturbances [65]