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In the context of metabolic disequilibrium, excessive lipid accumulation and mtROS activate the NLRP3 inflammasome in both hepatocytes and Kupffer cells

It boosts glutathione production, which supports the livers detoxification processes and protects against damage from toxins, alcohol and medications like acetaminophen

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In summary, the journey from a green to a red tomato is a vivid demonstration of precise genetic control over a defined enzymatic pathway, with PSY1 and LCY-B acting as critical gatekeepers

showed that low serum vitamin B 12 levels were observed in individuals taking metformin at doses over 2000 mg/day, and a prevalence of mild neuropathy reaching 22.3% in the metformin-users group compared to 15.1% in the non-metformin users group, consistent with the results of previous studies in the literature [49]

Ther 2001, 1, 923947