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10.3390/ijms24010415 122 SpencerE.RosengraveP.WillimanJ.ShawG.CarrA

These results indicate that NMs significantly enhanced lupeol production in callus cultures compared to their bulk counterparts

Kocsy et al., 1996

Many investigational agents have targeted mitochondrial function, including TUDCA [8, 149]

ER Ca 2+ release, sustained store-operated Ca 2+ entry, and persistent cytosolic Ca 2+ elevation can continue to damage PACs even when mitochondrial Ca 2+ entry through MCU is reduced, because calcium-dependent digestive enzyme activation, PM injury, and failure of ATP-dependent ion pumps remain operative