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2024a), the acute clinical severity can be catastrophic, involving aggressive systemic failure such as severe metabolic acidosis and renal shutdown

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Zhang, S., Wei, F., & Han, X

Free Radic Biol Med 22:471478 Liu F, Jan KY (2000) DNA damage in arsenite and cadmium treated bovine aortic endothelial cells

This initiates the downregulation of antiapoptotic proteins via the downstream MAP-kinase kinase MKK4/MKK7/JNK and MKK3/MKK6/p38 pathways (Saitoh et al