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thus, this review will also discuss current therapeutic strategies against hematological malignancies using existing small-molecule PAK inhibitors, as well as promising combination treatments, to sensitize drug-resistant cells to conventional therapies

505 After a three-year follow-up investigation, 54.1% and 56.3% of patients randomized to the ustekinumab q12w and q8w groups, respectively, achieved symptomatic relief at week 152 while on maintenance therapy

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As a result, they are able to prevent lipid peroxidation which is one of the most important actions of free radicals that leads to cellular membrane damage and, ultimately, to cell death [44]

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[DOI] [PMC free article] [PubMed] [Google Scholar] Schneider G., Kck H., Lindqvist Y