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In one published phase 2 study, adults with higher body weight were randomly assigned to once-weekly subcutaneous (under-the-skin) cagrilintide groups, including 0.3, 0.6, 1.2, 2.4, or 4.5 mg, along with comparator groups

Because all patients were treated with IL-17 or TNF inhibitors, we focused on DMPs in genes related to the IL-17/TNF pathway using the WikiPathways database (29)

According to a clinical study, three dietary intervention methods, including caloric limitation, intermittent fasting, and a ketogenic diet, positively intervene in mitochondrial respiratory function and increase cellular oxygen consumption rates

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