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Compared to mAChRs, nAChRs have a reduced affinity for the natural agonist ACh, which suggests that they may be involved in negative feedback mechanisms linked with growing levels of ACh

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Concurrently, EZH2 orchestrates epigenetic plasticity by directly remodeling histones or indirectly modulating chromatin regulators, fostering adaptive tolerance [43, 99]

European Biophysics Journal

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Il-1beta induces gfap expression in vitro and in vivo and protects neurons from traumatic injury-associated apoptosis in rat brain striatum via nfkappab/ca(2)(+)-calmodulin/erk mitogen-activated protein kinase signaling pathway