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Verburg et al

Nephrol Dial Transplant 2001, 16: 1483-1486

TDF treated patients were 1:1 propensity score (PS) matched to ETV treated patients on baseline age, sex, race/ethnicity, body-mass index (BMI), diabetes, hyperlipidemia, hypertension, alcohol abuse, HIV, cirrhosis, prior lamivudine treatment, creatinine, hepatitis B DNA and hepatitis B envelope antigen/antibody status

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High levels of lipid peroxidation-derived aldehydes, including 4-hydroxy-nonenal (4-HNE) and malondialdehyde (MDA) [92], protein glycoxidation markers such as pentosidine [93], and stress-induced DNA damage molecules, more specifically 8-hydroxy-2-deoxyguanosine (8-OHdG) [94, 95], have also been revealed in the spinal cord from sALS patients